
Deborah Perry Piscione is an operator, investor, and researcher who has spent three decades building companies, allocating capital, and studying the systems that drive — and destroy — economic value. When she speaks about AI-driven workforce displacement, she draws on original economic modeling, 100+ global engagements in 2025-2026, and a framework — the 500:1 Reckoning — that quantifies exactly what is at stake for every organization in the room.
She is the rare speaker who moves between the boardroom, the lecture hall, and the keynote stage with equal authority. A White House and Capitol Hill veteran turned Silicon Valley entrepreneur, NYT bestselling author of five books including Employment Is Dead (Harvard Business Review Press, 2025), and ranked #15 globally for AI and Future of Work by Clarity Group — Deborah has been building the future for 30 years.
*Source: Clarity Group (Australia)
FUTURIST + THOUGHT LEADER
AI + humanoids, web3 technologies, risk- taking + innovation
BOARD DIRECTOR + ADVISOR
SERIAL ENTREPRENEUR
INVESTOR
TV COMMENTATOR, GLOBAL SPEAKER + GUEST LECTURER
NEW YORK TIMES BESTSELLING AUTHOR
THINKERS50 (2025 Nominee)

Please see Deborah's Google Scholar page: https://scholar.google.com/citations?user=C-fhbuUAAAAJ&hl=en
Deborah's writing, research + podcasts with Harvard Business Review focuses on disruptive technologies and its impact on work + life.
Deborah's bottom's up innovation methodology Improvisational Innovation™ − an annual process that engages all the organization's talents in a safe and trusted environment. In the era of AI disruption, this methodology addresses a critical challenge: while AI automates routine innovation tasks, organizations need processes that unlock distinctly human capabilities—creativity, adaptive thinking, intuition, and judgment.
Deborah has served as a media commentator for MSNBC, FOX News, CNBC + CNN.



New ideas and bold bets are essential for the livelihood and survival of any organization operating in today’s competitive marketplace and era of exponential growth. On the minds of many leaders are questions like, “How do I know where the next big idea is?” and “What are the incremental or groundbreaking ideas that can be cultivated from my employees?” In this course, innovation thought leader Deborah Perry Piscione shares her bottom-up proprietary methodology that engages all the talents of the entire organization.
Want to become a great risk-taker? Without knowing when and how to take risks, you and your organization can lose market share, relevance, and potentially become obsolete. Risk-taking is one of the greatest leadership tools available and is imperative to the long-term growth of any organization. In this course, you as a leader have figured out how and when to take risks, you can then build a culture that not only focuses on producing the work, but also creates and executes a steady flow of ideas to improve every aspect of the organization.
CONTACT: KATY CALLAHAN, LEADING AUTHORITIES <katy@lauthorities.com>
https://www.leadingauthorities.com/speakers/deborah-perry-piscione
Copyright © 2026 Deborah Perry Piscione - All Rights Reserved.